ODCs

Click node...

2 OMIM references -
2 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
10 signs/symptoms

Dominant hypophosphatemia with nephrolithiasis or osteoporosis

Dubin-Johnson syndrome

SLC34A1	(UniProt - OMIM)		ABCC2	(UniProt - OMIM)
SLC9A3R1	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SLC9A3R1	(0.75)	ABCC2

Citations in the biomedical literature:

Dominant hypophosphatemia with nephrolithiasis or osteoporosis		Dubin-Johnson syndrome
	Synonym(s): (no synonyms)		Synonym(s): - Dubin-Sprinz disease - Hyperbilirubinemia type 2 - Sprinz-Nelson syndrome

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease - Rare renal disease		Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare hepatic disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: adolescence / young Average age of death: normal Type of inheritance: autosomal recessive

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D007566

Dubin-Johnson syndrome
	Very frequent - Abnormal colour of the urine / cholic / dark urines - Autosomal recessive inheritance - Hepatitis / icterus / cholestasis - Structural anomalies of the liver and the biliary tract Frequent - Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis Occasional - Acute abdominal pain / colic - Asthenia / fatigue / weakness - Clotting / hemostasis disorders - Fever / chilling - Hepatomegaly / liver enlargement (excluding storage disease)
Dominant hypophosphatemia with nephrolithiasis or osteoporosis
(no data available)